Data | Títol | Autor(s) | Tipus | 2022 | Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3 | Castellvi Toledo, Albert;Pequerul Pavon, Raquel;Barracco, Vito;Juanhuix, Judith;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2021 | Perspective on the structural basis for human aldo-keto reductase 1b10 inhibition | Pares Casasampera, Xavier;Farres Vicen, Jaime;Ruiz, Francesc Xavier | Article |
2021 | Design, Synthesis, Biological Evaluation and In Silico Study of Benzyloxybenzaldehyde Derivatives as Selective ALDH1A3 Inhibitors | Pares Casasampera, Xavier;Farres Vicen, Jaime;Ibrahim, Ali I. M.;Ikhmais, Balqis;Batlle, Elisabet;Abuharb, Waed K.;Jha, Vibhu;Jaradat, Khaled T.;Jiménez, Rafael;Pequerul, Raquel;Pors, Klaus | Article |
2019 | Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation | Pares Casasampera, Xavier;Farres Vicen, Jaime;Castellví Toledo, Albert;Crespo, Isidro;Crosas, Eva;Cámara-Artigas, Ana;Gavira, José A.;Aranda, Miguel A. G.;Juanhuix, Judith | Article |
2017 | Carbon-carbon double-bond hydrogenation of 15-deoxy-Δ12,14-prostaglandin J2 by human prostaglandin reductase 1: Product identification by 1H and 13C NMR spectroscopy and catalytic mechanism | Mesa, Julio;Porté, Sergio;Cabañas, Miquel;Jaime Cardiel, Carles;Pares Casasampera, Xavier;Virgili Moya, Albert | Article |
2016 | Enantioselective synthesis of vicinal R,R-diols by Saccharomyces cerevisiae butanediol dehydrogenase | Calam, Eduard;González-Roca, Eva;Fernandez Gallegos, Maria Rosario;Dequin, Sylvie;Pares Casasampera, Xavier;Virgili Moya, Albert;Biosca Vaque, Josep Antoni | Article |
2015 | Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10 | Ruiz, Francesc X.;Cousido-Siah, Alexandra;Domínguez, Marta;Crespo, Isidro;Rechlin, Chris;Mitschler, André;de Lera, Angel R.;Martín, María Jesús;De La Fuente, Jesús Ángel;Klebe, Gerhard;Pares Casasampera, Xavier;Farres Vicen, Jaime;Podjarny, Alberto | Article |
2015 | Substrate specificity, inhibitor selectivity and structure-function relationships of aldo-keto reductase 1B15: A novel human retinaldehyde reductase | Koláø, Michal H.;Ruiz, Francesc X.;Crespo, Isidro;Cousido-Siah, Alexandra;Podjarny, Alberto;Barski, Oleg A.;Fanfrlík, Jindøich;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2015 | Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10 | Cousido-Siah, Alexandra;Ruiz, Francesc X.;Crespo, Isidro;Mitschler, André;Pares Casasampera, Xavier;Podjarny, Alberto;Farres Vicen, Jaime | Article |
2015 | Human prostaglandin reductase 1 PGR1: Substrate specificity, inhibitor analysis and site-directed mutagenesis | Mesa, Julio;Alsina, Cristina;Oppermann, Udo;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2014 | The Xenopus alcohol dehydrogenase gene family: Characterization and comparative analysis incorporating amphibian and reptilian genomes | Albalat, Ricard;Duester, Gregg;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2014 | A missense mutation in ALDH1A3 causes isolated microphthalmia/anophthalmia in nine individuals from an inbred Muslim kindred | Mory, Adi;Ruiz, Francesc X.;Dagan, Efrat;Kurolap, Alina;Pares Casasampera, Xavier;Farres Vicen, Jaime;Gershoni-Baruch, Ruth | Article |
2014 | Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: Structure determination of both ternary complexes and implications for drug design | Cousido-Siah, Alexandra;Ruiz, Francesc X.;Mitschler, André;de Lera, Angel R.;Martin, Maria J.;Manzanaro, Sonia;De La Fuente, Jesús A.;Terwesten, Felix;Betz, Michael;Klebe, Gerhard;Farres Vicen, Jaime;Pares Casasampera, Xavier;Podjarny, Alberto | Article |
2013 | X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP+ and the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity | RUIZ, FX;COUSIDO-SIAH, A;MITSCHLER, A;Farres Vicen, Jaime;Pares Casasampera, Xavier;PODJARNY, A | Article |
2013 | Biocatalytic production of alpha-hydroxy ketones and vicinal diols by yeast and human aldo-keto reductases | Farres Vicen, Jaime;Fernandez Gallegos, Maria Rosario;Pares Casasampera, Xavier | Article |
2013 | Aldo-keto reductases in retinoid metabolism: Search for substrate specificity and inhibitor selectivity | PORTÉ, S;XAVIER, RUIZ F;Giménez, J.;MOLIST, I;Álvarez, S.;DOMÍNGUEZ, M;Álvarez, R.;DE, LERA AR;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2012 | Biological role of aldo-keto reductases in retinoic acid biosynthesis and signaling | Ruiz, F. Xavier;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2011 | Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin | Moeini ., Agrin;Reche, Irene;Shafqat, Naeem;Oppermann, Udo;Farres Vicen, Jaime;Pares Casasampera, Xavier | Article |
2011 | Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde | RUIZ, FX;MORO, A;Gallego, O;ARDÈVOL, A;Rovira, C.;PETRASH, JM;Pares Casasampera, Xavier;Farres Vicen, Jaime | Article |
2011 | Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily | Ruiz, F. Xavier;Gallego, Oriol;Moro, Armando;Ardèvol, Albert;Del Río-Espínola, Alberto;Rovira, Carme;Farres Vicen, Jaime;Pares Casasampera, Xavier | Article |