Mostrant 1 a 20 de 98 resultats
DataTítolAutor(s)Tipus
2022Amyloid-beta peptide and tau protein crosstalk in Alzheimer's diseaseVillegas Hernandez, Sandra;Ramos Roda, Alejandro;Montoliu-Gaya, Laia;Tiessler, LidiaArticle
2020Cognitive Impairment in the 3xTg-AD Mouse Model of Alzheimer's Disease is Affected by A beta-ImmunoTherapy and Cognitive StimulationRamos Roda, Alejandro;Villegas Hernandez, Sandra;Marti Clua, JoaquimArticle
2020Both Amyloid-β Peptide and Tau Protein Are Affected by an Anti-Amyloid-β Antibody Fragment in Elderly 3xTg-AD MiceSerra Mir, Gabriel;Villegas Hernandez, Sandra;Ramos Roda, Alejandro;Montoliu Gaya, LaiaArticle
2019Pharmacokinetic parameters and mechanism of action of an efficient anti-Aβ single chain antibody fragmentMarti Clua, Joaquim;Villegas Hernandez, SandraArticle
2019The Role of Apolipoprotein e Isoforms in Alzheimer's DiseaseRoda, Alejandro R.;Villegas Hernandez, SandraArticle
2019Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 LRP1-derived peptides against LDL aggregationBenitez-Amaro, Aleyda; Pallara, Chiara; Nasarre, Laura; Rivas-Urbina, Andrea; Benitez, Sonia; Vea, Angela; Bornachea, Olga; de Gonzalo-Calvo, David; Serra-Mir, Gabriel; Villegas, Sandra; Prades, Roger; Sanchez-Quesada, José Luís; Chiva, Cristina; Sabido, Eduard; Tarragó, Teresa; Llorente-Cortés, VicentaArticle
2019Treatment with scFv-h3D6 Prevented Neuronal Loss and Improved Spatial Memory in Young 3xTg-AD Mice by Reducing the Intracellular Amyloid-β BurdenRoda, Alejandro R.;Marti Clua, Joaquim;Rivera-Hernández, Geovanny;Villegas Hernandez, SandraArticle
2018Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD miceMontoliu-Gaya, L; Guell-Bosch, J; Esquerda-Canals, G; Roda, AR; Serra-Mir, G; Lope-Piedrafita, S; Villegas, S; Sanchez-Quesada, JLArticle
2018Aβ-oligomer uptake and the resulting inflammatory response in adult human astrocytes are precluded by an anti-Aβ single chain variable fragment in combination with an apoE mimetic peptideMulder, Sandra D.;Herrebout, Maaike A.C.;Baayen, Johannes C.;Villegas Hernandez, Sandra;Veerhuis, RobertArticle
2018Immunotherapy for neurodegenerative diseases: the Alzheimer's disease paradigmVillegas Hernandez, SandraArticle
2018La mort neuronal en Alzheimer es dona per l'acumulació intraneuronal del pèptid beta-amiloideVillegas Hernandez, SandraArticle
2017Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptidesMulder, Sandra D.;Veerhuis, Robert;Villegas Hernandez, SandraArticle
2017Production of an anti-Aβ antibody fragment in Pichia pastoris and in vitro and in vivo validation of its therapeutic effectVillegas Hernandez, SandraArticle
2017Towards the improvement in stability of an anti-Aβ single-chain variable fragment, scFv-h3D6, as a way to enhance its therapeutic potentialMurciano-Calles, Javier;Martinez, Jose C.;Villegas Hernandez, SandraArticle
2017Understanding the contribution of disulfide bridges to the folding and misfolding of an anti-Aβ scFvMartinez, Jose C.;Villegas Hernandez, SandraArticle
2017An intracellular amyloid-beta/AbetaPP epitope correlates with neurodegeneration in those neuronal populations early involved in Alzheimer's disease.Roda, Alejandro R.;Villegas Hernandez, SandraArticle
2017Mouse Models of Alzheimer's DiseaseVillegas Hernandez, SandraArticle
2017An Intracellular Amyloid-β/AβPP Epitope Correlates with Neurodegeneration in those Neuronal Populations Early Involved in Alzheimer's DiseaseMarti Clua, Joaquim;Roda, Alejandro R.;Villegas Hernandez, SandraArticle
2016The chondroitin sulfate/dermatan sulfate 4-O-endosulfatase from marine bacterium Vibrio sp FC509 is a dimeric species: Biophysical characterization of an endosulfataseNeira, José L.;Medina-Carmona, Encarnación;Hernández-Cifre, José G.;Cámara-Artigas, Ana;Seffouh, Ilham;Gonnet, Florence;Daniel, Régis;Villegas Hernandez, Sandra;de la Torre, José García;Pey, Angel L.;Li, FuchuanArticle
2016Functional inclusion bodies produced in the yeast Pichia pastorisRueda, Fabian;Gasser, Brigitte;Roldán, Mónica;Villegas Hernandez, Sandra;Puxbaum, Verena;Ferrer Miralles, Neus;Unzueta Elorza, Ugutz;Vazquez Gomez, Esther;Garcia Fruitós, Elena;Mattanovich, Diethard;Villaverde Corrales, Antonio PedroArticle